Data analysis results, performed by IBG researchers, using the SARS-Cov2 genome isolates in Turkey will be shared here.
IBG researchers have started covid-19 related research and development projects.
You can find the latest news on our contribution into the fight against Covid-19.
Identifying mutations in SARS-CoV-2, especially functional variants, and their distributions in the population, is crucial to successfully inoculate individuals against COVID-19, as well as to identify and treat new cases. Therefore, Doğa Eskier, Dr. Gökhan Karakülah and Dr. Yavuz Oktay from IBG sought to identify the distribution and variances of three major SARS-CoV-2 variants (B.1.1.7,
A group formed to investigate the mutation dynamics and evolution of the SARS-CoV-2 genome published their latest findings on the different selection dynamics of the S and RdRp genes in the Infection, Genetics and Evolution journal. doi.org/10.1016/j.meegid.2021.104796 The study includes a collaborative effort of Assist. Prof. Yavuz Oktay -group leader of Neuro-Genomics Lab at IBG-,
The manuscript with the title of; ‘Mutation density changes in SARS-CoV-2 are related to the pandemic stage but to a lesser extent in the dominant strain with mutations in spike and RdRp’, is just published in Biorxiv. (https://t.co/TY7Wve7Pdz) The study was conducted by Doğa Eskier -a PhD student at IBG-, and IBG group leaders Dr.s
Dr.s Yavuz Oktay and Gökhan Karakülah, research group leaders at IBG, and an IBG student Doğa Eskier have just published their in-silico analysis on the effects of SARS-Cov2 mutations on the viral properties and disease characteristics at Biorxiv (https://doi.org/10.1101/2020.05.20.104885). The researchers collaborated with Dr. Aslı Suner from Ege University. Viral genome sequences have been accumulating
To grant access to curated, comprehensive, and up-to-date information regarding SARS-CoV-2 isolates sequenced in Turkey and their mutatome to national and international researchers, in order to facilitate their efforts in fighting the continuing COVID-19 outbreak, IBG is proud to present an interactive map of the provinces of Turkey, which shows the number of isolates sequenced
Dr. Ezgi Karaca and the group members of the Karaca Lab at IBG, recently questioned whether in-silico prediction tools could foresee the impact of recently proposed ACE2 designer mutations. We know that ACE2 serves as the host receptor for the SARS-Cov2 virus. Spike proteins that are present on the surface of the virus membrane bind
Dr. Pavlopoulou, together with her collaborators from Italy and Greece, has just published their study on codon usage and evolutionary divergences of SARS-Cov2 genes in the internationally respected scientific journal, Viruses. The Covid-19 outbreak continues to dramatically impact people’s lives all around the world. New scientific understanding on the SARS-Cov2 virus genome is critical to
Multiple sequence alignment (MSA), whether peptide or nucleotide, can be stored in multiple formats, most commonly Clustal’s .aln format or the FASTA format. While these files are plain text files, and can be opened and edited in any text editor, performing many of the tasks common to MSA analysis in such editors is unintuitive and
The meeting started with an opening speech by Prof. Dr. Mandal on the importance of the fast and efficient continuation of scientific advances on Covid-19 in the fight against the outbreak and the mission of researchers in this fight. During the meeting, IBG researchers presented the content of their continuing Covid-19 projects and their preliminary
We estimated the full impact of the mutatome of 17 SARS-CoV-2 genomes isolated in Turkey, obtained from GISAID, on the tertiary structures of the coronavirus proteins. To this end, we employed multiple sequence alignment to identify changes in the amino acid sequences of 10 SARS-CoV-2 proteins, except surface glycoprotein, which we investigated in our previous
